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What is Sibutramine?
Sibutramine is manufactured by Abbott Laboratories, under brand names such as Reductil, Meridia and Sibutrex.
It is classified as a Schedule IV Controlled Substance in the United States, even though it has virtually no potential for abuse .
It is likely that the compound’s use as an anorectic is the sole reason is it classified as a controlled drug.
Anorectics (as a class) were over prescribed in the last 50 yrs and resulted in a number of cases of abuse or addiction.
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Here Is You Chemistry Lesson About Sibutramine Online
Sibutramine is a Neurotransmitter Reuptake Inhibitor.
It reduces the reuptake of:
Serotonin (by 53%),
Norepinephrine (by 54%),
Dopamine (by 16%),
This increases the levels of these substances within the neuron and enhances satiety.
The serotonergic action is thought to influence appetite.
Anorectic agents such as amphetamine and fenfluramine force the release of these neurotransmitters rather than affecting their reuptake.
It was approved by the FDA in Nov 1997 for the treatment of obesity.
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